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Accessed 1/6/17

Figure 2 illustrates schematically some documented changes: rhythms of locomotor activity (rest-activity cycle), core body temperature, hormone secretion (e.g., melatonin at night, cortisol in the morning), SCN neuronal firing rate, and even daily metabolic indicators like plasma glucose all show diminished oscillation amplitudes in older adults compared to younger adults

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However, research indicates that our natural levels of GHK-Cu decrease as we get older, dropping significantly by the time we hit age 60

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